CHRNA4 抗体 (N-Term)
(1 reference)-
- 抗原 See all CHRNA4 抗体
- CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 犬, 马, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHRNA4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AEERLLKKLF SGYNKWSRPV ANISDVVLVR FGLSIAQLID VDEKNQMMTT
- 预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against CHRNA4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNA4
- Top Product
- Discover our top product CHRNA4 Primary Antibody
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anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 49-242) antibody
CHRNA4 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 29-242) antibodyCHRNA4 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7B4H1 unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 531-627) antibodyCHRNA4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 176-208) antibodyCHRNA4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53684 unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 472-503) antibodyCHRNA4 适用: 人 WB 宿主: 兔 Polyclonal RB53481 unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) antibodyCHRNA4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (N-Term) antibodyCHRNA4 适用: 人, Cow, 豚鼠, 兔, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) antibodyCHRNA4 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) antibodyCHRNA4 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 1-451) antibodyCHRNA4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 627 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Involvement of nicotinic acetylcholine receptor in the proliferation of mouse induced pluripotent stem cells." in: Life sciences, Vol. 90, Issue 17-18, pp. 637-48, (2012) (PubMed).
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: "Involvement of nicotinic acetylcholine receptor in the proliferation of mouse induced pluripotent stem cells." in: Life sciences, Vol. 90, Issue 17-18, pp. 637-48, (2012) (PubMed).
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- 抗原
- CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))
- 别名
- CHRNA4 (CHRNA4 产品)
- 别名
- NACHRA4 antibody, BFNC antibody, EBN antibody, EBN1 antibody, NACHR antibody, NACRA4 antibody, NARAC antibody, Acra-4 antibody, Acra4 antibody, ENFL1 antibody, neuronal acetylcholine receptor subunit alpha-4 antibody, neuronal acetylcholine receptor subunit alpha-4-like antibody, cholinergic receptor nicotinic alpha 4 subunit antibody, cholinergic receptor, nicotinic, alpha 4b antibody, cholinergic receptor, nicotinic, alpha polypeptide 4 antibody, CpipJ_CPIJ002434 antibody, LOC100368057 antibody, CHRNA4 antibody, chrna4b antibody, Chrna4 antibody
- 背景
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CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BFNC, EBN, EBN1, NACRA4, NACHR, NACHRA4
Protein Interaction Partner: Ubqln1, CSNK2B, VSNL1, CHRNB4, CHRNB2, YWHAH, CRELD2,
Protein Size: 627 - 分子量
- 67 kDa
- 基因ID
- 1137
- NCBI登录号
- NM_000744, NP_000735
- UniProt
- P43681
- 途径
- Synaptic Membrane
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