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CHRNA4 抗体 (N-Term)

Name: CHRNA4 抗体 (N-Term)
SKU: ABIN2776101
Availability: OutOfStock

This anti-CHRNA4 antibody is a 兔多克隆 antibody detecting CHRNA4 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 犬, 马和斑马鱼. This Primary Antibody has been cited in 1 publication.

WB Suggested Anti-CHRNA4 Antibody Titration: 0. (CHRNA4 抗体 (N-Term))

1 image

(1 reference)

产品编号 ABIN2776101

发货至: 中国

Quick Overview for CHRNA4 抗体 (N-Term) (ABIN2776101)

抗原

See all CHRNA4 抗体

CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

适用

人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 犬, 马, 斑马鱼

宿主

兔

克隆类型

多克隆

标记

This CHRNA4 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product CHRNA4 Primary Antibody

抗原表位
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N-Term

序列

AEERLLKKLF SGYNKWSRPV ANISDVVLVR FGLSIAQLID VDEKNQMMTT

预测反应

Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 93%

产品特性

This is a rabbit polyclonal antibody against CHRNA4. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNA4
anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 49-242) antibody
CHRNA4 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 29-242) antibody
CHRNA4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7B4H1 unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 531-627) antibody
CHRNA4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 472-503) antibody
CHRNA4 适用: 人 WB 宿主: 兔 Polyclonal RB53481 unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 176-208) antibody
CHRNA4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53684 unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 29-43) antibody
Verified CHRNA4 适用: 人, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 36-85) antibody
CHRNA4 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 小鸡, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 1-451) antibody
CHRNA4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 29-128) antibody
CHRNA4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E3 unconjugated

anti-Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (AA 1-451) antibody
CHRNA4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 627 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Ishizuka, Ozawa, Goshima, Watanabe: "Involvement of nicotinic acetylcholine receptor in the proliferation of mouse induced pluripotent stem cells." in: Life sciences, Vol. 90, Issue 17-18, pp. 637-48, (2012) (PubMed).
抗原

CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

别名

CHRNA4

背景

CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BFNC, EBN, EBN1, NACRA4, NACHR, NACHRA4
Protein Interaction Partner: Ubqln1, CSNK2B, VSNL1, CHRNB4, CHRNB2, YWHAH, CRELD2,
Protein Size: 627

分子量

67 kDa

基因ID

1137

NCBI登录号

NM_000744, NP_000735

UniProt

P43681

途径

Synaptic Membrane