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THRA 抗体 (Middle Region)

This anti-THRA antibody is a 兔 多克隆 antibody detecting THRA in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 绵羊, 豚鼠 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2776019
发货至: 中国

Quick Overview for THRA 抗体 (Middle Region) (ABIN2776019)

抗原

See all THRA 抗体
THRA (Thyroid Hormone Receptor, alpha (THRA))

适用

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人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 绵羊, 豚鼠, 斑马鱼

宿主

  • 58
  • 29
  • 1

克隆类型

  • 59
  • 29
多克隆

标记

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  • 2
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This THRA antibody is un-conjugated

应用范围

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  • 14
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  • 1
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Western Blotting (WB)
  • 抗原表位

    • 16
    • 13
    • 9
    • 3
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    Middle Region

    序列

    DQIILLKGCC MEIMSLRAAV RYDPESDTLT LSGEMAVKRE QLKNGGLGVV

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against THRA. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human THRA
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 490 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kiss-Toth, Harlock, Lath, Quertermous, Wilkinson: "A TNF variant that associates with susceptibility to musculoskeletal disease modulates thyroid hormone receptor binding to control promoter activation." in: PLoS ONE, Vol. 8, Issue 9, pp. e76034, (2013) (PubMed).

  • 抗原

    THRA (Thyroid Hormone Receptor, alpha (THRA))

    别名

    THRA

    背景

    The THRA gene encodes a protein that is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone.
    Alias Symbols: AR7, EAR7, ERB-T-1, ERBA, ERBA1, MGC000261, MGC43240, NR1A1, THRA1, THRA2, c-ERBA-1, CHNG6
    Protein Interaction Partner: L3MBTL3, AMOTL2, RANBP9, NCOR1, PTGES3, THRA, RXRA, FOXJ1, CLIC1, C1D, NCOR2, BUB3, tat, GTF2B, ARID5A, SUMO1, SUMO3, MED1, NRIP1, MED21, CDK7, MED25, RGN, CUL1, SEPP1, TBL1XR1, HDAC3, SMC1A, XRCC5, TBL1X, PRKDC, LIG3, HSPA4, GPS2, XRCC6, PARP1, EMD, GRIP
    Protein Size: 490

    分子量

    55 kDa

    基因ID

    7067

    NCBI登录号

    NM_003250, NP_003241

    UniProt

    P10827

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development
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