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CREM 抗体 (C-Term)

The 兔 多克隆 anti-CREM antibody (ABIN2776017) specifically detects CREM in WB. The antibody is reactive with 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 绵羊 和 斑马鱼 samples.
产品编号 ABIN2776017
发货至: 中国
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Quick Overview for CREM 抗体 (C-Term) (ABIN2776017)

抗原

See all CREM 抗体
CREM (CAMP Responsive Element Modulator (CREM))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 绵羊, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This CREM antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    KNREAARECR RKKKEYVKCL ENRVAVLENQ NKTLIEELKA LKDLYCHKAE

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against Crem. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Rat Crem
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 357 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CREM (CAMP Responsive Element Modulator (CREM))

    别名

    Crem

    背景

    Crem is a transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Delta is an activator. Crem plays a role in spermatogenesis and is involved in spermatid maturation. Binding of isoform Tau (activator) to CRE is increased by CREB3L4. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE and may recruit HIRA to CRE to regulate histone exchange.
    Alias Symbols: Icer
    Protein Interaction Partner: Stub1, Ubc,
    Protein Size: 357

    分子量

    39 kDa

    基因ID

    25620

    NCBI登录号

    NM_001110860, NP_001104330

    UniProt

    Q03061

    途径

    Retinoic Acid Receptor Signaling Pathway
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