CREM 抗体 (N-Term)
(2 references)Quick Overview for CREM 抗体 (N-Term) (ABIN2776016)
抗原
See all CREM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MAAATGDMPT YQIRAPTAAL PQGVVMAASP GSLHSPQQLA EEATRKRELR
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against CREM. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CREM
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anti-CAMP Responsive Element Modulator (CREM) (AA 201-300) antibody
CREM 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-CAMP Responsive Element Modulator (CREM) (pSer287), (pSer290) antibodyCREM 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Modulator (CREM) (AA 145-321) antibodyCREM 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Modulator (CREM) (AA 1-137) antibodyCREM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Modulator (CREM) (Internal Region) antibodyCREM 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Modulator (CREM) (AA 287-314), (C-Term) antibodyCREM 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB17919 unconjugated
anti-CAMP Responsive Element Modulator (CREM) (AA 251-361) antibodyCREM 适用: 人, 小鼠 ELISA, IF (cc), IF (p), FACS, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Modulator (CREM) (AA 201-300) antibodyCREM 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-CAMP Responsive Element Modulator (CREM) (C-Term) antibodyVerified CREM 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-CAMP Responsive Element Modulator (CREM) (AA 19-68) antibodyCREM 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 绵羊, 山羊, Pig, Bat, 小鸡, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 120 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Methylation status of CpG islands flanking a cAMP response element motif on the protein phosphatase 2Ac alpha promoter determines CREB binding and activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1500-8, (2009) (PubMed).
: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
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: "Methylation status of CpG islands flanking a cAMP response element motif on the protein phosphatase 2Ac alpha promoter determines CREB binding and activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1500-8, (2009) (PubMed).
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- CREM (CAMP Responsive Element Modulator (CREM))
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别名
- CREM
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背景
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CREM is a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.
Alias Symbols: ICER, CREM-2, hCREM-2
Protein Interaction Partner: CREB1, PIAS3, CASP8AP2, UBE2I, UBC, SP100, ATXN1, EMP3, HHV8GK18_gp81, MAPK3, CREB3L4, HDAC1, CREB3L1, TAF4, CAMK2D, GSK3A, FHL5, GSK3B, KCNIP3, CAMK2G, PRKACA, CSNK1A1, CREBBP, TBP, PRKCA, SPI1, CREM, ATF1, CDC34, CDK1, CSNK2A2, CSNK2A1, CD34,
Protein Size: 120 -
分子量
- 13 kDa
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基因ID
- 1390
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NCBI登录号
- NM_182717, NP_874386
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UniProt
- O75519
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途径
- Retinoic Acid Receptor Signaling Pathway
抗原
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