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Forkhead Box K2 抗体 (Middle Region)

There is 1 publication for this product available. The 兔 多克隆 anti-Forkhead Box K2 antibody is suitable to detect Forkhead Box K2 in samples from 人, 小鼠, 大鼠, 兔, 马, Cow, Pig 和 犬. It has been validated for WB 和 IHC.
产品编号 ABIN2776014
发货至: 中国
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Quick Overview for Forkhead Box K2 抗体 (Middle Region) (ABIN2776014)

抗原

See all Forkhead Box K2 (FOXK2) 抗体
Forkhead Box K2 (FOXK2)

适用

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人, 小鼠, 大鼠, 兔, 马, Cow, Pig, 犬

宿主

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克隆类型

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多克隆

标记

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This Forkhead Box K2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    序列

    ANTYTVSGQA VVTPAAVLAP PKAEAQENGD HREVKVKVEP IPAIGHATLG

    预测反应

    Cow: 93%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 91%, Pig: 93%, Rabbit: 79%, Rat: 91%

    产品特性

    This is a rabbit polyclonal antibody against FOXK2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human FOXK2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 660 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Komorek, Kuppuswamy, Subramanian, Vijayalingam, Lomonosova, Zhao, Mymryk, Schmitt, Chinnadurai: "Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors." in: Journal of virology, Vol. 84, Issue 6, pp. 2719-31, (2010) (PubMed).

  • 抗原

    Forkhead Box K2 (FOXK2)

    别名

    FOXK2

    背景

    FOXK2 contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. Three alternatively spliced transcript variants encoding distinct isoforms have been described.The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
    Alias Symbols: ILF, ILF-1, ILF1
    Protein Interaction Partner: HECW2, SOX2, CBX6, SUMO2, BAP1, IRF2, AMOT, IL2,
    Protein Size: 660

    分子量

    69 kDa

    基因ID

    3607

    NCBI登录号

    NM_004514, NP_004505

    UniProt

    Q01167
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