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MIER1 抗体 (Middle Region)

The 兔 多克隆 anti-MIER1 antibody (ABIN183015) specifically detects MIER1 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 兔, 豚鼠 和 马 samples.
产品编号 ABIN183015
发货至: 中国
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Quick Overview for MIER1 抗体 (Middle Region) (ABIN183015)

抗原

See all MIER1 抗体
MIER1 (Mesoderm Induction Early Response 1 (MIER1))

适用

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人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 兔, 豚鼠, 马

宿主

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克隆类型

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多克隆

标记

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This MIER1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    RRTGDEKGVE AIPEGSHIKD NEQALYELVK CNFDTEEALR RLRF

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against MIER1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human MIER1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 536 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MIER1 (Mesoderm Induction Early Response 1 (MIER1))

    别名

    MIER1

    背景

    The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).
    Alias Symbols: ER1, MI-ER1, hMI-ER1, RP5-944N15.1
    Protein Interaction Partner: TMEM171, SOX2, HDAC2, HDAC1, EHMT2, CDYL, TUBB1, APP, ELAVL1, UBC, CREBBP, SP1,
    Protein Size: 536

    分子量

    49 kDa

    基因ID

    57708

    NCBI登录号

    NM_020948, NP_065999

    UniProt

    Q8NES5

    途径

    Chromatin Binding
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