MIER1 抗体 (Middle Region)
This anti-MIER1 antibody is a 兔 多克隆 antibody detecting MIER1 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 兔, 豚鼠 和 马.
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Quick Overview for MIER1 抗体 (Middle Region) (ABIN2775813)
抗原
See all MIER1 抗体
MIER1
(Mesoderm Induction Early Response 1 (MIER1))
适用
人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 兔, 豚鼠, 马
宿主
兔
克隆类型
多克隆
标记
This MIER1 antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- Middle Region
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序列
- RRTGDEKGVE AIPEGSHIKD NEQALYELVK CNFDTEEALR RLRF
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against MIER1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MIER1
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anti-Mesoderm Induction Early Response 1 (MIER1) (AA 250-293) antibody
MIER1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 兔, 豚鼠, 马, 小鸡, 非洲爪蟾, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 536 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MIER1 (Mesoderm Induction Early Response 1 (MIER1))
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别名
- MIER1
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背景
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The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).
Alias Symbols: ER1, MI-ER1, hMI-ER1, RP5-944N15.1
Protein Interaction Partner: TMEM171, SOX2, HDAC2, HDAC1, EHMT2, CDYL, TUBB1, APP, ELAVL1, UBC, CREBBP, SP1,
Protein Size: 536 -
分子量
- 49 kDa
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基因ID
- 57708
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NCBI登录号
- NM_020948, NP_065999
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UniProt
- Q8NES5
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途径
- Chromatin Binding
抗原
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