TRIM24 抗体 (Middle Region)
Quick Overview for TRIM24 抗体 (Middle Region) (ABIN2775799)
抗原
See all TRIM24 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- QQPSISHQQP PPRLINFQNH SPKPNGPVLP PHPQQLRYPP NQNIPRQAIK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%
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产品特性
- This is a rabbit polyclonal antibody against TRIM24. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TRIM24
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1050 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TRIM24 (Tripartite Motif Containing 24 (TRIM24))
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别名
- TRIM24
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背景
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The exact function of TRIM24 remains unknown. The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: PTC6, RNF82, TF1A, TIF1, TIF1A, TIF1ALPHA, hTIF1
Protein Interaction Partner: UBC, SUMO2, SUMO3, TRIM33, TP53, SUMO1, RNF2, RNF181, RNF141, ESR2, BRCA1, SF3B1, SF3B2, SNRPA, NONO, CDK12, NCOA1, TRIM8, NR3C2, ESR1, HIST1H3E, HIST2H4B, HIST4H4, HIST1H3F, HIST2H4A, HIST1H4L, HIST1H4E, HIST1H4B, HIST1H4H, HIST1H4C, HIST1H4J, HIST1H4K,
Protein Size: 1050 -
分子量
- 117 kDa
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基因ID
- 8805
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NCBI登录号
- NM_015905, NP_056989
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UniProt
- O15164
抗原
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