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CBX1 抗体 (N-Term)

This anti-CBX1 antibody is a 兔 多克隆 antibody detecting CBX1 in WB. Suitable for 人, 小鼠, 大鼠, 犬, Pig, Cow, 马, 兔, Saccharomyces cerevisiae 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2775787
发货至: 中国

Quick Overview for CBX1 抗体 (N-Term) (ABIN2775787)

抗原

See all CBX1 抗体
CBX1 (Chromobox Homolog 1 (CBX1))

适用

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人, 小鼠, 大鼠, 犬, Pig, Cow, 马, 兔, Saccharomyces cerevisiae, 斑马鱼

宿主

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  • 1

克隆类型

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多克隆

标记

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This CBX1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    MGKKQNKKKV EEVLEEEEEE YVVEKVLDRR VVKGKVEYLL KWKGFSDEDN

    预测反应

    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against CBX1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human CBX1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 185 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ayoub, Jeyasekharan, Bernal, Venkitaraman: "HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response." in: Nature, Vol. 453, Issue 7195, pp. 682-6, (2008) (PubMed).

  • 抗原

    CBX1 (Chromobox Homolog 1 (CBX1))

    别名

    CBX1

    背景

    CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the in
    Alias Symbols: CBX, HP1-BETA, HP1Hs-beta, M31, MOD1, p25beta, HP1Hsbeta
    Protein Interaction Partner: PRDM6, SUMO1, UBC, RNF2, PARK2, NR2F6, VHL, EHMT2, ABI3BP, VTN, TRIM39, CBX5, HIST1H3B, KLF11, HIST3H3, PCNA, MECP2, ADNP, POGZ, ADNP2, CBX3, TRIM28, CHAF1A, HIST1H4F, XRCC6, CHD4, H2AFB1, NSL1, SUMO2, HIST1H3A, Mad2l2, Cbx1, DNMT3B, ZNF382, H3F3A, SUV420
    Protein Size: 185

    分子量

    21 kDa

    基因ID

    10951

    NCBI登录号

    NM_006807, NP_006798

    UniProt

    P83916
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