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UBE2L3 抗体 (Middle Region)

The 兔 多克隆 anti-UBE2L3 antibody (ABIN2775682) specifically detects UBE2L3 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 和 斑马鱼 samples.
产品编号 ABIN2775682
发货至: 中国
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Quick Overview for UBE2L3 抗体 (Middle Region) (ABIN2775682)

抗原

See all UBE2L3 抗体
UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼

宿主

  • 71
  • 1
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克隆类型

  • 58
  • 15
多克隆

标记

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This UBE2L3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
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    Middle Region

    序列

    WQGLIVPDNP PYDKGAFRIE INFPAEYPFK PPKITFKTKI YHPNIDEKGQ

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against UBE2L3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human UBE2L3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 154 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

    别名

    UBE2L3

    背景

    UBE2L3 catalyzes the covalent attachment of ubiquitin to other proteins.It mediates the selective degradation of short-lived and abnormal proteins. UBE2L3 functions in the E6/E6-AP-induced ubiquitination of p53/TP53.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Alias Symbols: E2-F1, L-UBC, UBCH7, UbcM4
    Protein Interaction Partner: UBC, TRAF6, NEDD4, ITCH, MUL1, SMURF2, SMURF1, WWP2, WWP1, ARIH2, RNF144A, UBA1, PARK2, RNF144B, HACE1, ARIH1, UBE3A, UBE2L3, UBA6, UBR5, CACNA1B, MAP1LC3B, BAG3, HSPA4, AICDA, CCNB1IP1, FN1, RBX1, LIG4, ZPR1, USP9X, SF1, VDAC2, UCHL3, UBE2V2, UBE2D2, UBE
    Protein Size: 154

    分子量

    18 kDa

    基因ID

    7332

    NCBI登录号

    NM_003347, NP_003338

    UniProt

    Q5R5I4
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