UBE2I 抗体 (N-Term)
Quick Overview for UBE2I 抗体 (N-Term) (ABIN2775680)
抗原
See all UBE2I 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- MSGIALSRLA QERKAWRKDH PFGFVAVPTK NPDGTMNLMN WECAIPGKKG
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
-
产品特性
- This is a rabbit polyclonal antibody against UBE2I. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Protein A purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2I
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 158 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
-
别名
- UBE2I
-
背景
-
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2I is a member of the E2 ubiquitin-conjugating enzyme family.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: C358B7.1, P18, UBC9
Protein Interaction Partner: TRIM21, SP100, SUMO2, RANGAP1, PTEN, LMO2, PIAS2, TRIM23, PARP1, PIAS4, UBXN1, USP25, SETBP1, SIRT1, PUF60, HMGA1, GOLGA2, FHL3, ELK1, DES, DAXX, CREBBP, CLK2, RCBTB2, CEBPD, CBS, CAPN2, PPARGC1A, RFPL3, TRIM38, IKZF1, RNF40, XBP1, KRT19, HNRNPC, ZBTB8A,
Protein Size: 158 -
分子量
- 17 kDa
-
基因ID
- 7329
-
NCBI登录号
- NM_003345, NP_003336
-
UniProt
- P63279
-
途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Ubiquitin Proteasome Pathway
抗原
-