UBE2D3 抗体 (N-Term)
Quick Overview for UBE2D3 抗体 (N-Term) (ABIN2775674)
抗原
See all UBE2D3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MALKRINKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Yeast: 92%, Zebrafish: 92%
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产品特性
- This is a rabbit polyclonal antibody against UBE2D3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2D3
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anti-Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3) (AA 1-147) antibody
UBE2D3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C1-1E3 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3) (AA 1-147) antibodyUBE2D3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3) antibodyUBE2D3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3) (N-Term) antibodyUBE2D3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 小鸡, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3) (AA 1-100) antibodyUBE2D3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3) (AA 109-136), (C-Term) antibodyUBE2D3 适用: 人 WB 宿主: 兔 Polyclonal RB36300 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 147 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))
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别名
- UBE2D3
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背景
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
Alias Symbols: E2(17)KB3, MGC43926, MGC5416, UBC4/5, UBCH5C
Protein Interaction Partner: NHLRC1, DTX2, TRIM63, RNF146, RNF26, RBX1, UBC, RNF5, RNF2, NEDD4, MID1, STUB1, TRIM39, OTUB1, MDM2, RNF111, TRIM33, PRPF19, RNF115, TRIM58, BTRC, MARCH7, NFKBIA, ARIH1, FBXW11, UBE2D3, PARK2, BRCA1, BARD1, UBE3A, MSL1, UBA1, CBLC, SMURF1, RNF130, UBA6, M
Protein Size: 147 -
分子量
- 17 kDa
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基因ID
- 7323
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NCBI登录号
- NM_003340, NP_003331
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UniProt
- P61077
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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