RAG1 抗体 (C-Term)
Quick Overview for RAG1 抗体 (C-Term) (ABIN2775646)
抗原
See all RAG1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- IIERDGSIGA WASEGNESGN KLFRRFRKMN ARQSKCYEME DVLKHHWLYT
-
预测反应
- Horse: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
-
产品特性
- This is a rabbit polyclonal antibody against Rag1. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 1040 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- RAG1 (Recombination Activating Gene 1 (RAG1))
-
别名
- Rag1
-
背景
-
As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities.
Alias Symbols: Rag-1
Protein Interaction Partner: Gmeb1, Sf3a2, Kpna2, Rag1, UBE2C, UBE2H, UBE2E1, UBE2D2, UBE2D1, UBC, CDC34, Trav6-3, Rel, Nfkb1, Rela,
Protein Size: 1040 -
分子量
- 119 kDa
-
基因ID
- 19373
-
NCBI登录号
- NM_009019, NP_033045
-
UniProt
- P15919
抗原
-