RAG1 抗体 (C-Term)
Quick Overview for RAG1 抗体 (C-Term) (ABIN2775646)
抗原
See all RAG1 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- C-Term
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                                            序列
- IIERDGSIGA WASEGNESGN KLFRRFRKMN ARQSKCYEME DVLKHHWLYT
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                                            预测反应
- Horse: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
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                                            产品特性
- This is a rabbit polyclonal antibody against Rag1. It was validated on Western Blot.
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                                            纯化方法
- Affinity Purified
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                                            免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
 
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                                            应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            说明
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                        Antigen size: 1040 AA 
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- Lot specific
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                                            缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freeze-thaw cycles.
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                                            储存条件
- -20 °C
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                                            储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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    - RAG1 (Recombination Activating Gene 1 (RAG1))
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                                            别名
- Rag1
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                                            背景
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                        As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities.
 Alias Symbols: Rag-1
 Protein Interaction Partner: Gmeb1, Sf3a2, Kpna2, Rag1, UBE2C, UBE2H, UBE2E1, UBE2D2, UBE2D1, UBC, CDC34, Trav6-3, Rel, Nfkb1, Rela,
 Protein Size: 1040
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                                            分子量
- 119 kDa
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                                            基因ID
- 19373
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                                            NCBI登录号
- NM_009019, NP_033045
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                                            UniProt
- P15919
 抗原
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