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RAG1 抗体 (C-Term)

The 兔 多克隆 anti-RAG1 antibody is suitable to detect RAG1 in samples from 小鼠, Pig, 大鼠 和 马. It has been validated for WB.
产品编号 ABIN2775646
发货至: 中国
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Quick Overview for RAG1 抗体 (C-Term) (ABIN2775646)

抗原

See all RAG1 抗体
RAG1 (Recombination Activating Gene 1 (RAG1))

适用

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小鼠, Pig, 大鼠, 马

宿主

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克隆类型

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多克隆

标记

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This RAG1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    IIERDGSIGA WASEGNESGN KLFRRFRKMN ARQSKCYEME DVLKHHWLYT

    预测反应

    Horse: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against Rag1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide corresponding to a region of Mouse
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1040 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    RAG1 (Recombination Activating Gene 1 (RAG1))

    别名

    Rag1

    背景

    As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities.
    Alias Symbols: Rag-1
    Protein Interaction Partner: Gmeb1, Sf3a2, Kpna2, Rag1, UBE2C, UBE2H, UBE2E1, UBE2D2, UBE2D1, UBC, CDC34, Trav6-3, Rel, Nfkb1, Rela,
    Protein Size: 1040

    分子量

    119 kDa

    基因ID

    19373

    NCBI登录号

    NM_009019, NP_033045

    UniProt

    P15919
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