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AMOTL1 抗体 (N-Term)

This anti-AMOTL1 antibody is a 兔 多克隆 antibody detecting AMOTL1 in WB. Suitable for 人, 小鼠, Cow, 犬, 豚鼠 和 兔. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2775636
发货至: 中国

Quick Overview for AMOTL1 抗体 (N-Term) (ABIN2775636)

抗原

See all AMOTL1 抗体
AMOTL1 (Angiomotin Like 1 (AMOTL1))

适用

  • 35
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  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
人, 小鼠, Cow, 犬, 豚鼠, 兔

宿主

  • 31
  • 4

克隆类型

  • 33
  • 2
多克隆

标记

  • 21
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 2
This AMOTL1 antibody is un-conjugated

应用范围

  • 17
  • 12
  • 7
  • 4
  • 3
  • 3
  • 1
Western Blotting (WB)
  • 抗原表位

    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    LTQEDPQMVY QSARQEPQGQ EHQVDNTVME KQVRSTQPQQ NNEELPTYEE

    预测反应

    Cow: 93%, Dog: 79%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%

    产品特性

    This is a rabbit polyclonal antibody against AMOTL1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human AMOTL1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 956 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Skouloudaki, Walz: "YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation." in: PLoS ONE, Vol. 7, Issue 4, pp. e35735, (2012) (PubMed).

    Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

  • 抗原

    AMOTL1 (Angiomotin Like 1 (AMOTL1))

    别名

    AMOTL1

    背景

    AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.
    Alias Symbols: JEAP
    Protein Interaction Partner: WWOX, SUZ12, NEDD4, HECW2, AMOT, LATS2, YAP1, LATS1, Wwtr1, UBC, Magi1, NEDD4L,
    Protein Size: 956

    分子量

    106 kDa

    基因ID

    154810

    NCBI登录号

    NM_130847, NP_570899

    UniProt

    Q8IY63
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