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PARD6A 抗体 (N-Term)

This anti-PARD6A antibody is a 兔 多克隆 antibody detecting PARD6A in WB. Suitable for 人, 小鼠, 大鼠, Cow, 马, 兔, 豚鼠 和 犬.
产品编号 ABIN2775615
发货至: 中国

Quick Overview for PARD6A 抗体 (N-Term) (ABIN2775615)

抗原

See all PARD6A 抗体
PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

适用

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人, 小鼠, 大鼠, Cow, 马, 兔, 豚鼠, 犬

宿主

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克隆类型

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多克隆

标记

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This PARD6A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    MARPQRTPAR SPDSIVEVKS KFDAEFRRFA LPRASVSGFQ EFSRLLRAVH

    预测反应

    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against PARD6A. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PARD6A
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 345 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

    别名

    PARD6A

    背景

    This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40
    Protein Interaction Partner: PRKCI, WDR83, PRKCZ, FBXO31, PARD3, UBC, TUBG1, ARHGAP17, VHL, MAP2K5, TJP1, SMURF1, TGFB1, WDR92, PARD6B, PDRG1, RPAP3, MARK4, PIH1D1, SUGT1, YWHAZ, YWHAH, LLGL1, LLGL2, MARK2, CDC42, CRB3, ECT2, PLCB1, RHOQ, PRKCH, RAC1, CDH5, PLCB3, TGFBR1, TCP10, PRKC
    Protein Size: 345

    分子量

    37 kDa

    基因ID

    50855

    NCBI登录号

    NM_001037281, NP_001032358

    UniProt

    Q3TY70

    途径

    Cell-Cell Junction Organization
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