COX IV 抗体 (N-Term)
(3 references)Quick Overview for COX IV 抗体 (N-Term) (ABIN2775574)
抗原
See all COX IV (COX4I1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- AISTSVCVRA HESVVKSEDF SLPAYMDRRD HPLPEVAHVK HLSASQKALK
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 85%, Rabbit: 86%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against COX4I1. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human COX4I1
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anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) (AA 1-169) antibody
COX4I1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) (Center) antibodyCOX4I1 适用: 人 WB, IF, ICC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) (AA 59-169) antibodyCOX4I1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) (AA 51-169) antibodyCOX4I1 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) (AA 1-169) antibodyCOX4I1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4A10 unconjugated
anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) (AA 23-169) antibodyCOX4I1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) antibodyCOX4I1 适用: 人, 大鼠, 小鼠, 猴 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6B3 unconjugated
anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) antibodyCOX4I1 适用: 人, 大鼠 WB, IHC (p), IF (p) 宿主: 小鼠 Monoclonal 8D8 unconjugated
anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) antibodyCOX4I1 适用: 人, 大鼠, 小鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D4 unconjugated
anti-Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) (N-Term) antibodyCOX4I1 适用: 人, 小鼠, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 169 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome." in: Toxicology and applied pharmacology, (2016) (PubMed).
: "Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice." in: Diabetes, Vol. 63, Issue 3, pp. 880-91, (2014) (PubMed).
: "Mitochondrial ferritin in the substantia nigra in restless legs syndrome." in: Journal of neuropathology and experimental neurology, Vol. 68, Issue 11, pp. 1193-9, (2009) (PubMed).
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: "Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome." in: Toxicology and applied pharmacology, (2016) (PubMed).
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- COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))
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别名
- COX4I1
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背景
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Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. COX4I1 is the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme.Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.
Alias Symbols: COX4, COXIV, MGC72016, COX4-1
Protein Interaction Partner: SDCBP, COX1, env, APP, UBC, ICT1, TMBIM4, NELFCD,
Protein Size: 169 -
分子量
- 19 kDa
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基因ID
- 1327
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NCBI登录号
- NM_001861, NP_001852
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UniProt
- P13073
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途径
- Proton Transport
抗原
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