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Pannexin 2 抗体 (N-Term)

PANX2 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 马, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775571
发货至: 中国
  • 抗原 See all Pannexin 2 (PANX2) 抗体
    Pannexin 2 (PANX2)
    抗原表位
    • 8
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 26
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 斑马鱼, 马, Cow, 豚鼠
    宿主
    • 24
    • 4
    克隆类型
    • 24
    • 4
    多克隆
    标记
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    This Pannexin 2 antibody is un-conjugated
    应用范围
    • 22
    • 20
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    GTVLVPILLV TLVFTKNFAE EPIYCYTPHN FTRDQALYAR GYCWTELRDA
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against PANX2. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human PANX2
    Top Product
    Discover our top product PANX2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 633 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wicki-Stordeur, Boyce, Swayne: "Analysis of a pannexin 2-pannexin 1 chimeric protein supports divergent roles for pannexin C-termini in cellular localization." in: Cell communication & adhesion, Vol. 20, Issue 3-4, pp. 73-9, (2013) (PubMed).

    Mylvaganam, Zhang, Wu, Zhang, Samoilova, Eubanks, Carlen, Poulter: "Hippocampal seizures alter the expression of the pannexin and connexin transcriptome." in: Journal of neurochemistry, Vol. 112, Issue 1, pp. 92-102, (2010) (PubMed).

    Swayne, Sorbara, Bennett: "Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24977-86, (2010) (PubMed).

    Lai, Bechberger, Naus: "Pannexin2 as a novel growth regulator in C6 glioma cells." in: Oncogene, Vol. 28, Issue 49, pp. 4402-8, (2009) (PubMed).

    Wang, Streeter, Liu, Zhao: "Identification and characterization of pannexin expression in the mammalian cochlea." in: The Journal of comparative neurology, Vol. 512, Issue 3, pp. 336-46, (2008) (PubMed).

  • 抗原
    Pannexin 2 (PANX2)
    别名
    PANX2 (PANX2 产品)
    别名
    PANX2 antibody, si:ch211-192n14.2 antibody, PX2 antibody, hPANX2 antibody, pannexin 2 antibody, PANX2 antibody, LOC100533356 antibody, panx2 antibody, Panx2 antibody
    背景
    PANX2 belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties.The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties.
    Alias Symbols: hPANX2, PX2
    Protein Size: 633
    分子量
    70 kDa
    基因ID
    56666
    NCBI登录号
    NM_052839, NP_443071
    UniProt
    Q96RD6
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