Pannexin 2 抗体 (N-Term)
(5 references)Quick Overview for Pannexin 2 抗体 (N-Term) (ABIN2775571)
抗原
See all Pannexin 2 (PANX2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GTVLVPILLV TLVFTKNFAE EPIYCYTPHN FTRDQALYAR GYCWTELRDA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against PANX2. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PANX2
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anti-Pannexin 2 (PANX2) (AA 370-470) antibody
PANX2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pannexin 2 (PANX2) (AA 133-219) antibodyPANX2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Pannexin 2 (PANX2) (AA 57-106) antibodyPANX2 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 豚鼠, 马, Bat, 小鸡, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pannexin 2 (PANX2) (N-Term) antibodyPANX2 适用: 哺乳动物 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pannexin 2 (PANX2) (AA 76-90), (Extracellular) antibodyPANX2 适用: 人 WB, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 633 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Analysis of a pannexin 2-pannexin 1 chimeric protein supports divergent roles for pannexin C-termini in cellular localization." in: Cell communication & adhesion, Vol. 20, Issue 3-4, pp. 73-9, (2013) (PubMed).
: "Hippocampal seizures alter the expression of the pannexin and connexin transcriptome." in: Journal of neurochemistry, Vol. 112, Issue 1, pp. 92-102, (2010) (PubMed).
: "Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24977-86, (2010) (PubMed).
: "Pannexin2 as a novel growth regulator in C6 glioma cells." in: Oncogene, Vol. 28, Issue 49, pp. 4402-8, (2009) (PubMed).
: "Identification and characterization of pannexin expression in the mammalian cochlea." in: The Journal of comparative neurology, Vol. 512, Issue 3, pp. 336-46, (2008) (PubMed).
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: "Analysis of a pannexin 2-pannexin 1 chimeric protein supports divergent roles for pannexin C-termini in cellular localization." in: Cell communication & adhesion, Vol. 20, Issue 3-4, pp. 73-9, (2013) (PubMed).
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- Pannexin 2 (PANX2)
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别名
- PANX2
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背景
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PANX2 belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties.The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties.
Alias Symbols: hPANX2, PX2
Protein Size: 633 -
分子量
- 70 kDa
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基因ID
- 56666
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NCBI登录号
- NM_052839, NP_443071
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UniProt
- Q96RD6
抗原
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