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ACLY 抗体 (Middle Region)

Cited in 1 publication. This 兔 多克隆 anti-ACLY antibody specifically detects ACLY in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, Pig, Cow, 兔, 斑马鱼, 绵羊, 犬 和 马 samples.
产品编号 ABIN2775558
发货至: 中国
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Quick Overview for ACLY 抗体 (Middle Region) (ABIN2775558)

抗原

See all ACLY 抗体
ACLY (ATP Citrate Lyase (ACLY))

适用

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人, 小鼠, 大鼠, Pig, Cow, 兔, 斑马鱼, 绵羊, 犬, 马

宿主

  • 95
  • 14

克隆类型

  • 71
  • 38
多克隆

标记

  • 54
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This ACLY antibody is un-conjugated

应用范围

  • 90
  • 35
  • 27
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  • 21
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  • 11
  • 6
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 19
    • 15
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
    Middle Region

    序列

    LRSAYDSTME TMNYAQIRTI AIIAEGIPEA LTRKLIKKAD QKGVTIIGPA

    预测反应

    Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against ACLY. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ACLY
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1101 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Infantino, Iacobazzi, Palmieri, Menga: "ATP-citrate lyase is essential for macrophage inflammatory response." in: Biochemical and biophysical research communications, Vol. 440, Issue 1, pp. 105-11, (2013) (PubMed).

  • 抗原

    ACLY (ATP Citrate Lyase (ACLY))

    别名

    ACLY

    背景

    ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acety
    Alias Symbols: ACL, ATPCL, CLATP
    Protein Interaction Partner: UBC, UBR4, SIRT2, HUWE1, ISG15, KAT2B, SUMO2, SUMO3, STAU1, SUMO1, NEDD8, MDM2, ASB15, WWOX, TRIM25, MAGED2, BAG3, PPP6C, NCL, MCM6, MCM2, KPNA4, KPNA2, PRMT1, CDKN2A, SRRT, UBD, FN1, APP, SHC1, CUL3, CAND1, CUL2, SIRT7, UL27, HDAC5, TERF2, TERF1, GSK3B,
    Protein Size: 1101

    分子量

    121 kDa

    基因ID

    47

    NCBI登录号

    NM_001096, NP_001087

    UniProt

    P53396

    途径

    Warburg Effect
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