PLOD2 抗体 (Middle Region)
(1 reference)Quick Overview for PLOD2 抗体 (Middle Region) (ABIN2775556)
抗原
See all PLOD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- IKGKTLRSEM NERNYFVRDK LDPDMALCRN AREMTLQREK DSPTPETFQM
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PLOD2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PLOD2
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anti-Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) (AA 1-758) antibody
PLOD2 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) (AA 1-758) antibodyPLOD2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) (C-Term) antibodyPLOD2 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) (AA 470-650) antibodyPLOD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) (AA 467-516) antibodyPLOD2 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, Pig, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) (AA 644-737) antibodyPLOD2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) (AA 301-600) antibodyPLOD2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 758 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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- PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))
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别名
- PLOD2
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背景
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PLOD2 forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: LH2, TLH
Protein Interaction Partner: ITGB1BP2, SUPT5H, CSDE1, SF1, UGP2, TPP2, VASN, RNF123, NUSAP1, SAMHD1, DNPEP, GANAB, SWAP70, XPO7, PACSIN2, FAF1, HSPH1, SEC23A, PRMT3, FARSB, USP15, RANBP3, SET, RPL24, PTPN12, NCL, NARS, JUP, GART, XRCC6, AP2B1, gag-pol, UBL4A, OS9, FBXO6, UBC, VHL, Fa
Protein Size: 758 -
分子量
- 84 kDa
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基因ID
- 5352
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NCBI登录号
- NM_182943, NP_891988
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途径
- SARS-CoV-2 Protein Interactome
抗原
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