Caldesmon 抗体 (Middle Region)
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Quick Overview for Caldesmon 抗体 (Middle Region) (ABIN2775538)
抗原
See all Caldesmon (CALD1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- FSSPTAAGTP NKETAGLKVG VSSRINEWLT KTPDGNKSPA PKPSDLRPGD
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预测反应
- Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against CALD1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CALD1
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anti-Caldesmon 1 (CALD1) (AA 26-207) antibody
CALD1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6F8D2 unconjugated
anti-Caldesmon 1 (CALD1) (AA 434-531) antibodyCALD1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) (pSer789) antibodyCALD1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) (C-Term) antibodyCALD1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) antibodyCALD1 适用: 人, 大鼠 WB 宿主: 兔 Monoclonal CALD1-1424R unconjugated Recombinant Antibody
anti-Caldesmon 1 (CALD1) antibodyKD Validated CALD1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4735 unconjugated Recombinant Antibody
anti-Caldesmon 1 (CALD1) (AA 1-120) antibodyCALD1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) (AA 1-538) antibodyCALD1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) (AA 1-538) antibodyCALD1 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Caldesmon 1 (CALD1) antibodyCALD1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal CALD1-820 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 538 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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别名
- CALD1
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背景
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CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: CDM, H-CAD, L-CAD, MGC21352, NAG22, HCAD, LCAD
Protein Interaction Partner: TP53, RPA3, RPA2, RPA1, PHAX, FH, EPB41L2, CSNK2A1, LRCH3, PRKACA, PAN2, UBC, HSP90AA1, CALM1, ACTN1, TINF2, POT1, ISG15, TERF1, ARRB1, Poc1b, Cep76, Sass6, Pafah1b1, TERF2, SHC1, CDK1, CALM3, GRB2,
Protein Size: 538 -
分子量
- 63 kDa
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基因ID
- 800
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NCBI登录号
- NM_004342, NP_004333
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UniProt
- Q05682
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途径
- Myometrial Relaxation and Contraction
抗原
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