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Caldesmon 抗体 (Middle Region)

CALD1 适用: 人, 大鼠, 小鼠, 犬, 兔, 马, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775538
发货至: 中国
  • 抗原 See all Caldesmon (CALD1) 抗体
    Caldesmon (CALD1) (Caldesmon 1 (CALD1))
    抗原表位
    • 26
    • 15
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 85
    • 82
    • 63
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 犬, 兔, 马, Cow, 豚鼠
    宿主
    • 101
    • 19
    克隆类型
    • 84
    • 36
    多克隆
    标记
    • 74
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Caldesmon antibody is un-conjugated
    应用范围
    • 73
    • 32
    • 31
    • 27
    • 26
    • 19
    • 17
    • 17
    • 11
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    FSSPTAAGTP NKETAGLKVG VSSRINEWLT KTPDGNKSPA PKPSDLRPGD
    预测反应
    Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against CALD1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CALD1
    Top Product
    Discover our top product CALD1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 538 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Caldesmon (CALD1) (Caldesmon 1 (CALD1))
    别名
    CALD1 (CALD1 产品)
    别名
    CDM antibody, H-CAD antibody, HCAD antibody, L-CAD antibody, LCAD antibody, NAG22 antibody, l-Cad antibody, 4833423D12Rik antibody, AI195384 antibody, AV071549 antibody, AW536160 antibody, C920027I18Rik antibody, CALD1 antibody, Caldesmon antibody, caldesmon 1 antibody, CALD1 antibody, Cald1 antibody
    背景
    CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
    Alias Symbols: CDM, H-CAD, L-CAD, MGC21352, NAG22, HCAD, LCAD
    Protein Interaction Partner: TP53, RPA3, RPA2, RPA1, PHAX, FH, EPB41L2, CSNK2A1, LRCH3, PRKACA, PAN2, UBC, HSP90AA1, CALM1, ACTN1, TINF2, POT1, ISG15, TERF1, ARRB1, Poc1b, Cep76, Sass6, Pafah1b1, TERF2, SHC1, CDK1, CALM3, GRB2,
    Protein Size: 538
    分子量
    63 kDa
    基因ID
    800
    NCBI登录号
    NM_004342, NP_004333
    UniProt
    Q05682
    途径
    Myometrial Relaxation and Contraction
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