S1PR5 抗体 (N-Term)
(1 reference)Quick Overview for S1PR5 抗体 (N-Term) (ABIN2775524)
抗原
See all S1PR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MESGLLRPAP VSEVIVLHYN YTGKLRGARY QPGAGLRADA VVCLAVCAFI
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预测反应
- Cow: 80%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against EDG8. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human EDG8
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anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (AA 1-200) antibody
S1PR5 适用: 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (AA 1-50) antibodyS1PR5 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴, Opossum WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (AA 309-398) antibodyS1PR5 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (N-Term) antibodyS1PR5 适用: 人, 大鼠, Pig, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (C-Term) antibodyS1PR5 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (N-Term) antibodyS1PR5 适用: 人, 小鼠, 大鼠, 犬, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (N-Term) antibodyS1PR5 适用: 人, 小鼠, 大鼠, 犬, Pig, 猴, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (N-Term) antibodyS1PR5 适用: 人, 小鼠, 大鼠, 犬, Drosophila melanogaster, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) (AA 24-39), (Extracellular) antibodyS1PR5 适用: 小鼠 WB, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 5 (S1PR5) antibodyS1PR5 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 147 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells." in: Journal of dermatological science, Vol. 82, Issue 1, pp. 9-17, (2016) (PubMed).
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: "Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells." in: Journal of dermatological science, Vol. 82, Issue 1, pp. 9-17, (2016) (PubMed).
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- S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
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别名
- EDG8
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背景
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EDG8 is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. It Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). It may play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
Alias Symbols: Edg-8, S1P5, S1PR5, SPPR-1, SPPR-2, EDG8
Protein Interaction Partner: TP63, GNA12, GNAO1, GNAI1, SGPP1,
Protein Size: 147 -
分子量
- 16 kDa
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基因ID
- 53637
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NCBI登录号
- NM_003339
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UniProt
- Q9H228
抗原
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