ANO1 抗体 (Middle Region)
Quick Overview for ANO1 抗体 (Middle Region) (ABIN2775453)
抗原
See all ANO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- HGFVNHTLSS FNVSDFQNGT APNDPLDLGY EVQICRYKDY REPPWSENKY
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against TMEM16A. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TMEM16A
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 960 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Characterization of the effects of Cl⁻ channel modulators on TMEM16A and bestrophin-1 Ca²⁺ activated Cl⁻ channels." in: Pflügers Archiv : European journal of physiology, Vol. 467, Issue 7, pp. 1417-1430, (2015) (PubMed).
: "Epinephrine stimulation of anion secretion in the Calu-3 serous cell model." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 10, pp. L937-46, (2014) (PubMed).
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: "Characterization of the effects of Cl⁻ channel modulators on TMEM16A and bestrophin-1 Ca²⁺ activated Cl⁻ channels." in: Pflügers Archiv : European journal of physiology, Vol. 467, Issue 7, pp. 1417-1430, (2015) (PubMed).
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- ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
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别名
- TMEM16A
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背景
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TMEM16A belongs to the anoctamin family. TMEM16A acts as a calcium-activated chloride channel. It is required for normal tracheal development.
Alias Symbols: FLJ10261, ORAOV2, TAOS2, CACC, DOG1, TMEM16A, ANO1
Protein Interaction Partner: UBC,
Protein Size: 960 -
分子量
- 111 kDa
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基因ID
- 55107
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NCBI登录号
- NM_018043, NP_060513
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UniProt
- Q5XXA6
抗原
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