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ANO1 抗体 (Middle Region)

Cited in 2+ publications. This 兔 多克隆 anti-ANO1 antibody specifically detects ANO1 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 和 兔 samples.
产品编号 ABIN2775453
发货至: 中国
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Quick Overview for ANO1 抗体 (Middle Region) (ABIN2775453)

抗原

See all ANO1 抗体
ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

适用

  • 160
  • 33
  • 24
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔

宿主

  • 101
  • 63

克隆类型

  • 97
  • 66
  • 1
多克隆

标记

  • 64
  • 14
  • 7
  • 7
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This ANO1 antibody is un-conjugated

应用范围

  • 74
  • 57
  • 55
  • 50
  • 30
  • 21
  • 20
  • 16
  • 13
  • 13
  • 9
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 26
    • 15
    • 8
    • 8
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    HGFVNHTLSS FNVSDFQNGT APNDPLDLGY EVQICRYKDY REPPWSENKY

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against TMEM16A. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human TMEM16A
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 960 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Liu, Zhang, Huang, Qi, Xu, Gao, Du, Gamper, Zhang: "Characterization of the effects of Cl⁻ channel modulators on TMEM16A and bestrophin-1 Ca²⁺ activated Cl⁻ channels." in: Pflügers Archiv : European journal of physiology, Vol. 467, Issue 7, pp. 1417-1430, (2015) (PubMed).

    Banga, Flaig, Lewis, Winfree, Blazer-Yost: "Epinephrine stimulation of anion secretion in the Calu-3 serous cell model." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 10, pp. L937-46, (2014) (PubMed).

  • 抗原

    ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

    别名

    TMEM16A

    背景

    TMEM16A belongs to the anoctamin family. TMEM16A acts as a calcium-activated chloride channel. It is required for normal tracheal development.
    Alias Symbols: FLJ10261, ORAOV2, TAOS2, CACC, DOG1, TMEM16A, ANO1
    Protein Interaction Partner: UBC,
    Protein Size: 960

    分子量

    111 kDa

    基因ID

    55107

    NCBI登录号

    NM_018043, NP_060513

    UniProt

    Q5XXA6
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