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MFN2 抗体 (C-Term)

Name: MFN2 抗体 (C-Term)
SKU: ABIN2775408
Availability: OutOfStock

This anti-MFN2 antibody is a 兔多克隆 antibody detecting MFN2 in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, 兔, Cow, 犬, 豚鼠, 马和斑马鱼. This Primary Antibody has been cited in 1 publication.

WB Suggested Anti-MFN2 Antibody Titration: 0. (MFN2 抗体 (C-Term))

Rabbit Anti-MFN2 Antibody Formalin Fixed Paraffin Embedded Tissue: Human Heart Tissue Observed Staining: Cytoplasm in cardiomyocytes Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (MFN2 抗体 (C-Term))

IHC

2 images

(1 reference)

产品编号 ABIN2775408

发货至: 中国

Quick Overview for MFN2 抗体 (C-Term) (ABIN2775408)

抗原

See all MFN2 抗体

MFN2 (Mitofusin 2 (MFN2))

适用

人, 大鼠, 小鼠, 兔, Cow, 犬, 豚鼠, 马, 斑马鱼

宿主

兔

克隆类型

多克隆

标记

This MFN2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product MFN2 Primary Antibody

抗原表位
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C-Term

序列

LEQEIAAMNK KIEVLDSLQS KAKLLRNKAG WLDSELNMFT HQYLQPSR

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

产品特性

This is a rabbit polyclonal antibody against MFN2. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human MFN2
anti-Mitofusin 2 (MFN2) (AA 661-757) antibody
MFN2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 4H8 unconjugated

anti-Mitofusin 2 (MFN2) (AA 1-120) antibody
MFN2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 500-600) antibody
MFN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 687-757) antibody
MFN2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 447-476) antibody
MFN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (N-Term) antibody
MFN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody
MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 unconjugated

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (HRP)
MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 HRP

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (FITC)
MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 FITC

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Biotin)
MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 Biotin

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 757 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Siu, Zhou, Yu, Zhang, Wang, Liang, Chen, Chan, Yu: "Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation." in: Scientific reports, Vol. 6, pp. 23464, (2016) (PubMed).
抗原

MFN2 (Mitofusin 2 (MFN2))

别名

MFN2

背景

MFN2 is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. It is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke.This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Alias Symbols: CMT2A, CMT2A2, CPRP1, HSG, KIAA0214, MARF
Protein Interaction Partner: UBC, MARCH5, PARK2, UBE2N, MFN2, TER94, MAVS, vpr, HUWE1, MAPK9,
Protein Size: 757

分子量

86 kDa

基因ID

9927

NCBI登录号

NM_014874, NP_055689

UniProt

O95140

途径

Skeletal Muscle Fiber Development