PPP2R3B 抗体 (C-Term)
(1 reference)Quick Overview for PPP2R3B 抗体 (C-Term) (ABIN2775379)
抗原
See all PPP2R3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- TFFNIEKYLD HEQKEQISLL RDGDSGGPEL SDWEKYAAEE YDILVAEETA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 77%, Horse: 77%, Human: 100%, Mouse: 77%, Rabbit: 77%, Rat: 82%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against PPP2R3B. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PPP2R3B
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anti-Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B) (AA 1-225) antibody
PPP2R3B 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 2E12 unconjugated
anti-Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B) (AA 356-575), (Regulatory Subunit B) antibodyPPP2R3B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B) (AA 1-176) antibodyPPP2R3B 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1F4 unconjugated
anti-Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B) (AA 1-225) antibodyPPP2R3B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B) (AA 1-176) antibodyPPP2R3B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B) (Internal Region) antibodyPPP2R3B 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B) (AA 356-575), (Regulatory Subunit B) antibodyPPP2R3B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B) (AA 470-519) antibodyPPP2R3B 适用: 人, 犬, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B) antibodyPPP2R3B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B) (AA 1-176) antibodyPPP2R3B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 575 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene. ..." in: Science translational medicine, Vol. 8, Issue 369, pp. 369ra177, (2016) (PubMed).
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: "The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene. ..." in: Science translational medicine, Vol. 8, Issue 369, pp. 369ra177, (2016) (PubMed).
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- PPP2R3B (Protein Phosphatase 2A 48 KDa Regulatory Subunit (PPP2R3B))
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别名
- PPP2R3B
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背景
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Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. PPP2R3B belongs to the B'' family. The B'' family has been further divided into subfamilies. PPP2R3B belongs to the beta subfamily of regulatory subunit B''.Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: NY-REN-8, PPP2R3L, PPP2R3LY, PR48, NYREN8
Protein Interaction Partner: DUSP12, UBC, PPP2R1A, CDC6, PPP2R1B, PPP2CA,
Protein Size: 575 -
分子量
- 65 kDa
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基因ID
- 28227
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NCBI登录号
- NM_013239, NP_037371
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UniProt
- Q9Y5P8
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途径
- PI3K-Akt Signaling, Mitotic G1-G1/S Phases
抗原
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