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SNCA 抗体 (Middle Region)

This 兔多克隆 antibody specifically detects SNCA in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, 绵羊, 犬, 兔, 马和豚鼠.

Host: Rabbit Target Name: FAM46C Sample Type: Human Fetal Liver Antibody Dilution: 1. (SNCA 抗体 (Middle Region))

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产品编号 ABIN2775366

发货至: 中国

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中国
北京 101111

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Quick Overview for SNCA 抗体 (Middle Region) (ABIN2775366)

抗原

See all SNCA 抗体

SNCA (Synuclein, alpha (SNCA))

适用

人, 小鼠, 大鼠, Cow, 绵羊, 犬, 兔, 马, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This SNCA antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product SNCA Primary Antibody

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Middle Region

原理

SNCA Antibody - middle region

序列

VTNVGGAVVT GVTAVAQKTV EGAGSIAAAT GFVKKDQLGK EGYQDYEPEA

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

产品特性

This is a rabbit polyclonal antibody against SNCA. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human SNCA
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (FITC)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal FITC

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Biotin)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Biotin

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (HRP)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal HRP

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (PE)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal PE

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (PerCP)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal PerCP

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Atto 488)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 488

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Atto 390)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 390

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (APC)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal APC

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Atto 594)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 594

应用备注

Optimal working dilution should be determined by the investigator.

说明

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42350-100UG

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

prevent freeze-thaw cycles

储存条件

4 °C,-20 °C

储存方法

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
抗原

SNCA (Synuclein, alpha (SNCA))

别名

SNCA

背景

Background Information: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease.Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Two alternatively spliced transcripts of SNCA have been identified. Additional splicing may be present but the full-length nature of these variants has not been determined.
Gene Name: Synuclein, alpha (non A4 component of amyloid precursor)
Alternative Symbols: PD1, NACP, PARK1, PARK4
Protein Name: Alpha-synuclein

分子量

11kDa

基因ID

6622

NCBI登录号

NP_009292

UniProt

P37840

途径

Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity