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Cytokeratin 1 抗体 (Middle Region)

This anti-Cytokeratin 1 antibody is a 兔 多克隆 antibody detecting Cytokeratin 1 in WB 和 IHC. Suitable for 人, 大鼠, 兔 和 犬.
产品编号 ABIN2775333
发货至: 中国

Quick Overview for Cytokeratin 1 抗体 (Middle Region) (ABIN2775333)

抗原

See all Cytokeratin 1 (KRT1) 抗体
Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

适用

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人, 大鼠, 兔, 犬

宿主

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  • 58
  • 1

克隆类型

  • 69
  • 68
多克隆

标记

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This Cytokeratin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 20
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    Middle Region

    序列

    GSYGSGSSSG GYRGGSGGGG GGSSGGRGSG GGSSGGSIGG RGSSSGGVKS

    预测反应

    Dog: 86%, Human: 100%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against KRT1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human KRT1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 644 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

    别名

    KRT1

    背景

    KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CK1, EHK1, K1, KRT1A, EHK, EPPK, NEPPK
    Protein Interaction Partner: MDM2, LGR4, EED, ESR1, ADRB2, PAN2, Iqcb1, Nphp4, Cep290, Nphp1, Invs, GRDX, VCAM1, UBC, ITGA4, FN1, CDH1, APOA1, ALB, MAGOH, EIF4A3, KRT10, KRT9, KRT2, SLC25A5, SHC1, PIK3R2, INPPL1, GRB2, EPS15, CRK, AP2M1, CBL, UBASH3B, NEDD8, CAND1, DCUN1D1, COPS5, CO
    Protein Size: 644

    分子量

    66 kDa

    基因ID

    3848

    NCBI登录号

    NM_006121, NP_006112

    UniProt

    P04264
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