IDH3A 抗体 (N-Term)
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北京 101111
Quick Overview for IDH3A 抗体 (N-Term) (ABIN2775312)
抗原
See all IDH3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MKIFDAAKAP IQWEERNVTA IQGPGGKWMI PSEAKESMDK NKMGLKGPLK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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产品特性
- This is a rabbit polyclonal antibody against IDH3A. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human IDH3A
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anti-Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) (AA 28-366) antibody
IDH3A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) antibodyIDH3A 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) antibodyIDH3A 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) (AA 281-366) antibodyIDH3A 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) (AA 28-108) antibodyIDH3A 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) (C-Term) antibodyVerified IDH3A 适用: 人, 大鼠, 小鼠, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) (AA 1-366) antibodyIDH3A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) (Internal Region) antibodyIDH3A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) antibodyIDH3A 适用: 人, 犬 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) antibodyIDH3A 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 366 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy." in: Scientific reports, Vol. 2, pp. 785, (2012) (PubMed).
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: "Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy." in: Scientific reports, Vol. 2, pp. 785, (2012) (PubMed).
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- IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))
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别名
- IDH3A
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背景
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Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. IDH3A is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
Protein Interaction Partner: HUWE1, SUMO2, STAU1, UBC, MDM2, ADRB2, gag-pol, RAB4A, MBNL1, S100A16, SUCLA2, UQCRFS1P1, SUMO4, EBNA-LP, MYC, TERF2, TERF1, PSMD4, DDA1, DMWD, IDH3B, IDH3G,
Protein Size: 366 -
分子量
- 40 kDa
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基因ID
- 3419
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NCBI登录号
- NM_005530, NP_005521
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UniProt
- P50213
抗原
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