CD8B 抗体 (Middle Region)
Quick Overview for CD8B 抗体 (Middle Region) (ABIN2775291)
抗原
See all CD8B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- KPEDSGIYFC MIVGSPELTF GKGTQLSVVD FLPTTAQPTK KSTLKKRVCR
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预测反应
- Dog: 79%, Human: 100%, Rabbit: 93%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against CD8B. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CD8B
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 210 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CD8B (CD8b Molecule (CD8B))
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别名
- CD8B
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背景
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The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8B is the CD8 beta chain isoforms.
Alias Symbols: CD8B1, LYT3, Leu2, Ly3, MGC119115, LY3, P37, LEU2
Protein Interaction Partner: ELAVL1, CD8A, CD3D, CD8B, ST3GAL4, LCK,
Protein Size: 210 -
分子量
- 21 kDa
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基因ID
- 926
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NCBI登录号
- NM_004931, NP_004922
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UniProt
- P10966
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途径
- TCR Signaling
抗原
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