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CD8B 抗体 (Middle Region)

This anti-CD8B antibody is a 兔 多克隆 antibody detecting CD8B in WB. Suitable for 人, 大鼠, 犬 和 兔.
产品编号 ABIN2775291
发货至: 中国

Quick Overview for CD8B 抗体 (Middle Region) (ABIN2775291)

抗原

See all CD8B 抗体
CD8B (CD8b Molecule (CD8B))

适用

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  • 33
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人, 大鼠, 犬, 兔

宿主

  • 76
  • 61
  • 22

克隆类型

  • 81
  • 77
  • 1
多克隆

标记

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This CD8B antibody is un-conjugated

应用范围

  • 81
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Western Blotting (WB)
  • 抗原表位

    • 15
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    Middle Region

    序列

    KPEDSGIYFC MIVGSPELTF GKGTQLSVVD FLPTTAQPTK KSTLKKRVCR

    预测反应

    Dog: 79%, Human: 100%, Rabbit: 93%, Rat: 85%

    产品特性

    This is a rabbit polyclonal antibody against CD8B. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human CD8B
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 210 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CD8B (CD8b Molecule (CD8B))

    别名

    CD8B

    背景

    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8B is the CD8 beta chain isoforms.
    Alias Symbols: CD8B1, LYT3, Leu2, Ly3, MGC119115, LY3, P37, LEU2
    Protein Interaction Partner: ELAVL1, CD8A, CD3D, CD8B, ST3GAL4, LCK,
    Protein Size: 210

    分子量

    21 kDa

    基因ID

    926

    NCBI登录号

    NM_004931, NP_004922

    UniProt

    P10966

    途径

    TCR Signaling
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