CD8B 抗体 (N-Term)
Quick Overview for CD8B 抗体 (N-Term) (ABIN2775290)
抗原
See all CD8B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- RIYWLRQRQA PSSDSHHEFL ALWDSAKGTI HGEEVEQEKI AVFRDASRFI
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预测反应
- Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against CD8B. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CD8B
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anti-CD8b Molecule (CD8B) (AA 51-150) antibody
CD8B 适用: 人 WB, ELISA, IHC (fro), ICC, IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD8b Molecule (CD8B) antibodyCD8B 适用: 大鼠 FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal 341 unconjugated
anti-CD8b Molecule (CD8B) antibody (FITC)CD8B 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal 341 FITC
anti-CD8b Molecule (CD8B) antibody (PE)CD8B 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal 341 PE
anti-CD8b Molecule (CD8B) (AA 22-170) antibodyCD8B 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD8b Molecule (CD8B) (AA 22-170) antibodyCD8B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD8b Molecule (CD8B) (AA 1-243) antibodyCD8B 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD8b Molecule (CD8B) antibodyCD8B 适用: 大鼠 FACS, WB, IP, IHC (fro), Func 宿主: 小鼠 Monoclonal 341 unconjugated
anti-CD8b Molecule (CD8B) antibody (PE)CD8B 适用: Cow, 绵羊, 山羊, Water Buffalo FACS 宿主: 小鼠 Monoclonal CC58 PE
anti-CD8b Molecule (CD8B) antibody (PE)CD8B 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal H35-17-2 PE
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 246 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CD8B (CD8b Molecule (CD8B))
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别名
- CD8B
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背景
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The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8B is the CD8 beta chain isoforms.The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
Alias Symbols: CD8B, LYT3, Leu2, Ly3, LY3, P37, LEU2, CD8B1
Protein Interaction Partner: ELAVL1, CD8A, CD3D, CD8B, ST3GAL4, LCK,
Protein Size: 246 -
分子量
- 27 kDa
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基因ID
- 926
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NCBI登录号
- NM_172099, NP_742097
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UniProt
- Q53QL8
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途径
- TCR Signaling
抗原
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