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IFIH1 抗体 (Middle Region)

This anti-IFIH1 antibody is a 兔 多克隆 antibody detecting IFIH1 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 马 和 Pig.
产品编号 ABIN2775253
发货至: 中国

Quick Overview for IFIH1 抗体 (Middle Region) (ABIN2775253)

抗原

See all IFIH1 抗体
IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))

适用

  • 44
  • 13
  • 3
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Cow, 马, Pig

宿主

  • 37
  • 8
  • 2

克隆类型

  • 36
  • 11
多克隆

标记

  • 41
  • 3
  • 2
  • 1
This IFIH1 antibody is un-conjugated

应用范围

  • 37
  • 23
  • 22
  • 12
  • 8
  • 7
  • 7
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    QINDTIRMID AYTHLETFYN EEKDKKFAVI EDDSDEGGDD EYCDGDEDED

    预测反应

    Cow: 85%, Horse: 85%, Human: 100%, Mouse: 77%, Pig: 77%, Rat: 82%

    产品特性

    This is a rabbit polyclonal antibody against IFIH1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human IFIH1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1025 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))

    别名

    IFIH1

    背景

    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. IFIH1 is a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: Hlcd, IDDM19, MDA-5, MDA5, MGC133047
    Protein Interaction Partner: USP21, USP3, UBC, NLRC5, APP, TSPAN6, MAVS, PCBP2, PIAS2, SUMO1, IDE,
    Protein Size: 1025

    分子量

    117 kDa

    基因ID

    64135

    NCBI登录号

    NM_022168, NP_071451

    UniProt

    Q9BYX4

    途径

    Activation of Innate immune Response
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