RAD54B 抗体 (Middle Region)
Quick Overview for RAD54B 抗体 (Middle Region) (ABIN2775216)
抗原
See all RAD54B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- NSLKPLSMSQ LKQWKHFSGD HLNLTDPFLE RITENVSFIF QNITTQATGT
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against RAD54B. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RAD54B
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 910 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RAD54B (DNA repair and recombination protein RAD54B (RAD54B))
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别名
- RAD54B
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背景
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RAD54B belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
Alias Symbols: FSBP, RDH54
Protein Interaction Partner: TCEANC, ATPAF2, ANKRD36BP1, ENKD1, MYO15B, GMCL1, RAD54B, CDC23, SUMO1, PRKAA1, FUS, HECW2, PSMA1, RAD51, NUDT18, NIF3L1, TCEB3, COPS6, SUMO2, UBC, WRN, ZNF580, LNX1, TRAPPC6A, RIBC2, CCDC33, UBE2I, GORASP2, DYRK2, DMC1, CSNK1E, CD2BP2,
Protein Size: 910 -
分子量
- 103 kDa
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基因ID
- 25788
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NCBI登录号
- NM_012415, NP_036547
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UniProt
- Q9Y620
抗原
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