INTS6 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for INTS6 抗体 (C-Term) (ABIN2775213)
抗原
See all INTS6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- INTS6 Antibody - C-terminal region
-
序列
- GFLENHEEPR DKEQCAEENI PASSLNKGKK LMHCRSHEEV NTELKAQIMK
-
预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%
-
产品特性
- This is a rabbit polyclonal antibody against INTS6. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human INTS6
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36404-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- INTS6 (Integrator Complex Subunit 6 (INTS6))
-
别名
- INTS6
-
背景
-
Targeted Subunit: 6
Background Information: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. INTS6 is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.
Gene Name: Integrator complex subunit 6
Alternative Symbols: HDB, INT6, DBI-1, DDX26, DICE1, DDX26A, Notchl2
-
分子量
- 99kDa
-
基因ID
- 26512
-
NCBI登录号
- NP_001035026
-
UniProt
- A8MV98
抗原
-