INTS6 抗体 (C-Term)
Quick Overview for INTS6 抗体 (C-Term) (ABIN2775213)
抗原
See all INTS6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- GFLENHEEPR DKEQCAEENI PASSLNKGKK LMHCRSHEEV NTELKAQIMK
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against INTS6. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human INTS6
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 874 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- INTS6 (Integrator Complex Subunit 6 (INTS6))
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别名
- INTS6
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背景
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. INTS6 is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: DBI-1, DDX26, DDX26A, DICE1, DKFZP434B105, HDB, INT6, Notchl2
Protein Interaction Partner: RPA3, RPA2, RPA1, BMI1, UBC, MCM7, INTS10, CTDP1, SHFM1, DDX26B, NAIF1, INTS4, VWA9, INTS5, NABP2, C7orf26, INTS3, ZNF687, INTS2, INTS12, INTS9, ASUN, INTS8, CPSF3L, INTS6, INTS1, INTS7, ZMYND8, ZNF592, PPP2R1B, PPP2R1A, PPP2CB, PPP2CA, PPP1CB, POLR2L, PO
Protein Size: 874 -
分子量
- 99 kDa
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基因ID
- 26512
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NCBI登录号
- NM_001039937, NP_001035026
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UniProt
- A8MV98
抗原
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