AKAP1 抗体 (C-Term)
Quick Overview for AKAP1 抗体 (C-Term) (ABIN405082)
抗原
See all AKAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- VPFSNGVLKG ELSDLGAEDG WTMDAEADHS GVAAPPPGKR GTLITRCPGF
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against AKAP1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human AKAP1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 593 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))
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别名
- AKAP1
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背景
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP1 is a member of the AKAP family. It binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.
Alias Symbols: AKAP, AKAP121, AKAP149, AKAP84, D-AKAP1, MGC1807, PRKA1, SAKAP84, PPP1R43
Protein Interaction Partner: MDM2, PRKACB, PRKACA, UBC, APP, TP73, USP7, PPP1CA, MYCBP, PTPN21, CAV1, PRKAR1A, PRKAR2B, PRKAR1B, PRKAR2A, AMY1C, SIAH2, MAATS1, AMY1A,
Protein Size: 593 -
分子量
- 65 kDa
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基因ID
- 8165
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NCBI登录号
- NM_139275, NP_644804
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UniProt
- Q92667
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途径
- Synaptic Membrane
抗原
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