AKAP10 抗体 (Middle Region)
Quick Overview for AKAP10 抗体 (Middle Region) (ABIN2775175)
抗原
See all AKAP10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- ESLYQRTYAG KMTFGRVSDL GQFIRESEPE PDVRKSKGSM FSQAMKKWVQ
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预测反应
- Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 90%
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产品特性
- This is a rabbit polyclonal antibody against AKAP10. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human AKAP10
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 662 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))
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别名
- AKAP10
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背景
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA, therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.
Alias Symbols: D-AKAP2, MGC9414, PRKA10
Protein Interaction Partner: COG3, DCTN4, MYH9, PRKAR1A, HAX1, SLC9A3R1, PDZK1, PRKAR2B, PRKAR2A,
Protein Size: 662 -
分子量
- 71 kDa
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基因ID
- 11216
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NCBI登录号
- NM_007202, NP_009133
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UniProt
- O43572
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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