CTCFL 抗体 (N-Term)
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北京 101111
Quick Overview for CTCFL 抗体 (N-Term) (ABIN501510)
抗原
See all CTCFL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- CREKDHRSPS ELEAERTSGA FQDSVLEEEV ELVLAPSEES EKYILTLQTV
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against CTCFL. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CTCFL
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anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (N-Term) antibody
CTCFL 适用: 人 WB, ChIP-seq, ChIP 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-270) antibodyCTCFL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 617-650) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal RB54304 unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-636) antibodyCTCFL 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-270) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 36-85) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 211-260) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 663 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation." in: Cancer research, Vol. 68, Issue 8, pp. 2726-35, (2008) (PubMed).
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- CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
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别名
- CTCFL
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背景
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CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. CTCFL is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and CTCFL are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation.CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BORIS, CTCF-T, MGC163358, dJ579F20.2, CT27, HMGB1L1
Protein Interaction Partner: SP1, BAG6, HIST2H2AC, HIST1H1A, PRMT7, HIST1H3A, BRCA1,
Protein Size: 663 -
分子量
- 76 kDa
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基因ID
- 140690
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NCBI登录号
- NM_080618, NP_542185
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UniProt
- Q8NI51
抗原
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