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JMJD2D 抗体 (C-Term)

There are 2+ publications for this product available. The 兔 多克隆 anti-JMJD2D antibody is suitable to detect JMJD2D in samples from 人. It has been validated for WB.
产品编号 ABIN183251
发货至: 中国
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Quick Overview for JMJD2D 抗体 (C-Term) (ABIN183251)

抗原

See all JMJD2D (KDM4D) 抗体
JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))

适用

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宿主

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克隆类型

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多克隆

标记

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This JMJD2D antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    SSTPGPSAQI IHPSNGRRGR GRPPQKLRAQ ELTLQTPAKR PLLAGTTCTA

    预测反应

    Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against JMJD2D. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human JMJD2D
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 523 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kim, Fuchs, Schwartz, Abdelhamid, Etter, Berry, Li, Ihnat, Li, Janknecht: "Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors." in: American journal of translational research, Vol. 6, Issue 3, pp. 236-47, (2014) (PubMed).

    Kim, Oh, Shin, Janknecht: "Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D." in: PLoS ONE, Vol. 7, Issue 4, pp. e34618, (2012) (PubMed).

  • 抗原

    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))

    别名

    JMJD2D

    背景

    JMJD2D belongs to JMJD2 family that is consist of four cancer-associated genes
    Alias Symbols: JMJD2D
    Protein Interaction Partner: HECW2, PPP1CC, CUL4B, TP53, AR, KDM4D,
    Protein Size: 523

    分子量

    59 kDa

    基因ID

    55693

    NCBI登录号

    NM_018039, NP_060509

    UniProt

    Q6B0I6

    途径

    Warburg Effect
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