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WWP1 抗体 (N-Term)

The 兔 多克隆 anti-WWP1 antibody is suitable to detect WWP1 in samples from 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马 和 Pig. It has been validated for WB 和 IHC.
产品编号 ABIN2774928
发货至: 中国
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Quick Overview for WWP1 抗体 (N-Term) (ABIN2774928)

抗原

See all WWP1 抗体
WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

适用

人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, Pig

宿主

  • 21
  • 7

克隆类型

  • 23
  • 5
多克隆

标记

  • 21
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This WWP1 antibody is un-conjugated

应用范围

  • 17
  • 8
  • 5
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    ATASPRSDTS NNHSGRLQLQ VTVSSAKLKR KKNWFGTAIY TEVVVDGEIT

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against WWP1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human WWP1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 922 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

    别名

    WWP1

    背景

    WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. WWP1 is a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. WWP1 belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes.WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants, however, the full length nature of these transcripts has not been defined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: AIP5, DKFZp434D2111, Tiul1, hSDRP1
    Protein Interaction Partner: SMAD3, FBXL18, WWP1, TRAF4, FAM189A2, UBE2L3, UBC, PTCH1, SMAD6, NOTCH1, EZH2, YWHAQ, CPSF6, TRAF6, LAPTM5, SMAD5, HSP90AA1, FBXL15, H2AFY2, PHF20L1, RNF11, ASH2L, PRKAA2, ATN1, LNX1, TP63, PTPN14, ERBB4, NFE2, SMAD7, SMAD4, SMAD2, SMAD1, RUNX2, Axin1, ga
    Protein Size: 922

    分子量

    105 kDa

    基因ID

    11059

    NCBI登录号

    NM_007013, NP_008944

    UniProt

    Q9H0M0
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