WWP1 抗体 (N-Term)
Quick Overview for WWP1 抗体 (N-Term) (ABIN2774928)
抗原
See all WWP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ATASPRSDTS NNHSGRLQLQ VTVSSAKLKR KKNWFGTAIY TEVVVDGEIT
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against WWP1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human WWP1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 922 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
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别名
- WWP1
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背景
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WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. WWP1 is a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. WWP1 belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes.WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants, however, the full length nature of these transcripts has not been defined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AIP5, DKFZp434D2111, Tiul1, hSDRP1
Protein Interaction Partner: SMAD3, FBXL18, WWP1, TRAF4, FAM189A2, UBE2L3, UBC, PTCH1, SMAD6, NOTCH1, EZH2, YWHAQ, CPSF6, TRAF6, LAPTM5, SMAD5, HSP90AA1, FBXL15, H2AFY2, PHF20L1, RNF11, ASH2L, PRKAA2, ATN1, LNX1, TP63, PTPN14, ERBB4, NFE2, SMAD7, SMAD4, SMAD2, SMAD1, RUNX2, Axin1, ga
Protein Size: 922 -
分子量
- 105 kDa
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基因ID
- 11059
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NCBI登录号
- NM_007013, NP_008944
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UniProt
- Q9H0M0
抗原
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