UBE2E3 抗体 (N-Term)
Quick Overview for UBE2E3 抗体 (N-Term) (ABIN2774921)
抗原
See all UBE2E3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MSSDRQRSDD ESPSTSSGSS DADQRDPAAP EPEEQEERKP SATQQKKNTK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against UBE2E3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2E3
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 207 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UBE2E3 (Ubiquitin-Conjugating Enzyme E2E 3 (UBE2E3))
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别名
- UBE2E3
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背景
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100 % sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: UBCH9, UbcM2
Protein Interaction Partner: RNF185, MUL1, TRIM39, RNF5, MID1, RNF25, MARCH5, UBE2E3, UBA1, TARDBP, UBC, HTT, ITCH, HERC4, NEDD4L, WWP2, RNF14, RNF8, MDM2, BRCA1, BARD1, KLHL42, RCBTB1, CUL1, CUL3, CUL4A, SPOP, ATXN1, ARID3A, RCBTB2, MOT2, CNOT4, NFE2L2, MID2, TRIM38, TRIM27, TRIM37,
Protein Size: 207 -
分子量
- 23 kDa
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基因ID
- 10477
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NCBI登录号
- NM_006357, NP_006348
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UniProt
- Q969T4
抗原
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