RNF6 抗体 (C-Term)
Quick Overview for RNF6 抗体 (C-Term) (ABIN2774919)
抗原
See all RNF6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- VETGTLPILR LAHFFLLNES DDDDRIRGLT KEQIDNLSTR HYEHNSIDSE
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 86%, Rat: 92%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against RNF6. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RNF6
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 685 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RNF6 (RING Finger Protein 6 (RNF6))
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别名
- RNF6
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背景
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RNF6 contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
Alias Symbols: DKFZp686P0776
Protein Interaction Partner: UBE2D1, AR, LDB1, UBC, tat, UBE2H,
Protein Size: 685 -
分子量
- 78 kDa
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基因ID
- 6049
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NCBI登录号
- NM_005977, NP_005968
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UniProt
- Q9Y252
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size
抗原
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