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Annexin VII 抗体 (N-Term)

This anti-Annexin VII antibody is a 兔 多克隆 antibody detecting Annexin VII in WB. Suitable for 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠 和 马. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2774843
发货至: 中国

Quick Overview for Annexin VII 抗体 (N-Term) (ABIN2774843)

抗原

See all Annexin VII (ANXA7) 抗体
Annexin VII (ANXA7) (Annexin A7 (ANXA7))

适用

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人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马

宿主

  • 60
  • 3
  • 1

克隆类型

  • 61
  • 3
多克隆

标记

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This Annexin VII antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    MSYPGYPPTG YPPFPGYPPA GQESSFPPSG QYPYPSGFPP MGGGAYPQVP

    预测反应

    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against ANXA7. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA7
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 466 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Satoh, Nakano, Shibata, Maki: "The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent manner." in: Biochimica et biophysica acta, Vol. 1600, Issue 1-2, pp. 61-7, (2002) (PubMed).

  • 抗原

    Annexin VII (ANXA7) (Annexin A7 (ANXA7))

    别名

    ANXA7

    背景

    ANXA7 is a member of the annexin family of calcium-dependent phospholipid binding proteins. The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. The selection of poly(A) signals is independent of the mRNA splicing pattern. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.
    Alias Symbols: SNX, ANX7, SYNEXIN
    Protein Interaction Partner: UBC, PAX8, ATP4A, SRC, Prkcb, Prkcg, Prkca, PRKG1, PRKACA, VCP, ANXA4, CUL4B, CUL5, ALG2, ELAVL1, CCDC90B, WDR18, LRIF1, OTUB1, CPSF3L, SEMA5B, INPP5K, ACTL6B, CSAD, SDF4, MED31, TAF5L, TRMT2A, TUBB2B, CPNE2, ZNF431, KLHL23, DOCK7, WDR73, FBN3, RBM48, ADA
    Protein Size: 466

    分子量

    51 kDa

    基因ID

    310

    NCBI登录号

    NM_001156, NP_001147

    UniProt

    Q5T0M6
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