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Annexin a1 抗体 (N-Term)

Cited in 2+ publications. The 兔 多克隆 anti-Annexin a1 antibody (ABIN2774833) specifically detects Annexin a1 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, 豚鼠, 犬 和 Cow samples.
产品编号 ABIN2774833
发货至: 中国
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Quick Overview for Annexin a1 抗体 (N-Term) (ABIN2774833)

抗原

See all Annexin a1 (ANXA1) 抗体
Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

适用

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人, 小鼠, 大鼠, 豚鼠, 犬, Cow

宿主

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兔

克隆类型

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多克隆

标记

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This Annexin a1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    原理

    ANXA1 Antibody - N-terminal region

    序列

    WFIENEEQEY VQTVKSSKGG PGSAVSPYPT FNPSSDVAAL HKAIMVKGVD

    预测反应

    Cow: 79%, Dog: 79%, Guinea Pig: 79%, Human: 100%, Mouse: 83%, Rat: 82%

    产品特性

    This is a rabbit polyclonal antibody against ANXA1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36568-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Ishida, Yamasaki, Yukizaki, Nishiyama, Tsubouchi, Okayama, Kataoka et al.: "Carnosol, rosemary ingredient, induces apoptosis in adult T-cell leukemia/lymphoma cells via glutathione depletion: proteomic approach using fluorescent two-dimensional differential gel ..." in: Human cell, Vol. 27, Issue 2, pp. 68-77, (2014) (PubMed).

    Nordon, Hinchliffe, Malkawi, Pirianov, Torsney, Loftus, Cockerill, Thompson: "Comparative proteomics reveals a systemic vulnerability in the vasculature of patients with abdominal aortic aneurysms." in: Journal of vascular surgery, Vol. 54, Issue 4, pp. 1100-1108.e6, (2011) (PubMed).

  • 抗原

    Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

    别名

    ANXA1

    背景

    Background Information: ANXA1 encodes a protein that belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

    Gene Name: Annexin A1

    Alternative Symbols: ANX1, LPC1

    Protein Name: Annexin RuleBase RU003540

    分子量

    39 kDa

    基因ID

    301

    NCBI登录号

    NP_000691

    UniProt

    P04083

    途径

    Hormone Transport
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