TRIM63 抗体 (Middle Region)
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北京 101111
Quick Overview for TRIM63 抗体 (Middle Region) (ABIN2774803)
抗原
See all TRIM63 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- TRIM63 Antibody - middle region
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序列
- EQLDKSTKLV ETAIQSLDEP GGATFLLTAK QLIKSIVEAS KGCQLGKTEQ
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against TRIM63. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TRIM63
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43365-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TRIM63 (Tripartite Motif Containing 63 (TRIM63))
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别名
- TRIM63
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背景
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Background Information: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.
Gene Name: Tripartite motif containing 63, E3 ubiquitin protein ligase
Alternative Symbols: IRF, SMRZ, MURF1, MURF2, RNF28
Protein Name: E3 ubiquitin-protein ligase TRIM63
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分子量
- 40kDa
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基因ID
- 84676
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NCBI登录号
- NP_115977
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UniProt
- Q969Q1
抗原
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