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RNF31 抗体 (Middle Region)

Cited in 8+ publications. The 兔 多克隆 anti-RNF31 antibody (ABIN2774753) specifically detects RNF31 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马 和 Cow samples.
产品编号 ABIN2774753
发货至: 中国
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Quick Overview for RNF31 抗体 (Middle Region) (ABIN2774753)

抗原

See all RNF31 抗体
RNF31 (Ring Finger Protein 31 (RNF31))

适用

人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, Cow

宿主

  • 38
  • 1
  • 1

克隆类型

  • 40
多克隆

标记

  • 17
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RNF31 antibody is un-conjugated

应用范围

  • 35
  • 15
  • 13
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    SLINAHSLDP ATLYEVEELE TATERYLHVR PQPLAGEDPP AYQARLLQKL

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against RNF31. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human RNF31
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1072 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Shibata, Tokunaga, Goto, Komatsu, Gohda, Saeki, Tanaka, Takahashi, Sawasaki, Inoue, Oshiumi, Seya, Nakano, Tanaka, Iwai, Inoue: "HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains." in: PLoS pathogens, Vol. 13, Issue 1, pp. e1006162, (2017) (PubMed).

    Lafont, Kantari-Mimoun, Draber, De Miguel, Hartwig, Reichert, Kupka, Shimizu, Taraborrelli, Spit, Sprick, Walczak: "The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death." in: The EMBO journal, Vol. 36, Issue 9, pp. 1147-1166, (2017) (PubMed).

    Kupka, De Miguel, Draber, Martino, Surinova, Rittinger, Walczak: "SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes." in: Cell reports, Vol. 16, Issue 9, pp. 2271-80, (2016) (PubMed).

    Queisser, Dada, Deiss-Yehiely, Angulo, Zhou, Kouri, Knab, Liu, Stegh, DeCamp, Budinger, Chandel, Ciechanover, Iwai, Sznajder: "HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth." in: American journal of respiratory and critical care medicine, Vol. 190, Issue 6, pp. 688-98, (2014) (PubMed).

    Blackwell, Zhang, Workman, Ting, Iwai, Habelhah: "Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed I?B kinase activation." in: Molecular and cellular biology, Vol. 33, Issue 10, pp. 1901-15, (2013) (PubMed).

    Liu, Chen, Cai, Wu, Chen, Wu, Sun, Chen: "MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades." in: eLife, Vol. 2, pp. e00785, (2013) (PubMed).

    Smit, Monteferrario, Noordermeer, van Dijk, van der Reijden, Sixma: "The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension." in: The EMBO journal, Vol. 31, Issue 19, pp. 3833-44, (2012) (PubMed).

    Sieber, Lange, Kollmorgen, Erhardt, Quaas, Gontarewicz, Sass, Tiegs, Kreienkamp: "Sharpin contributes to TNF? dependent NF?B activation and anti-apoptotic signalling in hepatocytes." in: PLoS ONE, Vol. 7, Issue 1, pp. e29993, (2012) (PubMed).

  • 抗原

    RNF31 (Ring Finger Protein 31 (RNF31))

    别名

    RNF31

    背景

    PWP2 contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.
    Alias Symbols: FLJ10111, FLJ23501, MGC19975, ZIBRA, HOIP
    Protein Interaction Partner: CCDC24, VASN, KRTAP9-2, TSSC4, UBC, SNRPC, PRKCA, AES, PITX1, KIF1A, SHARPIN, RBCK1, RNF31, MALT1, VCP, OTULIN, IRAK1, ESR1, Ikbkg, CCDC14, WRNIP1, AKAP8L, TRAF2, TNF, NDUFA8, BIRC2, NOD2, BIRC3, HCVgp1, SOCS3, SMAD3, NOS3, UBE2D3, UBE2D1, TNFAIP3, GFI1B,
    Protein Size: 1072

    分子量

    120 kDa

    基因ID

    55072

    NCBI登录号

    NM_017999, NP_060469

    UniProt

    Q96EP0
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