MARCH5 抗体 (N-Term)
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北京 101111
Quick Overview for MARCH5 抗体 (N-Term) (ABIN2774746)
抗原
See all MARCH5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- MARCH5 Antibody - N-terminal region
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序列
- CRGSTKWVHQ ACLQRWVDEK QRGNSTARVA CPQCNAEYLI VFPKLGPVVY
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against MARCH5. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MARCH5
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anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) (AA 4-32), (N-Term) antibody
MARCH5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB21862 unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) (C-Term) antibodyMARCH5 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 豚鼠, 马, 兔, 小鸡, Bat, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) (AA 1-95) antibodyMARCH5 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) (AA 1-95) antibodyMARCH5 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C3 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43232-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy." in: Biochimica et biophysica acta, Vol. 1843, Issue 7, pp. 1295-307, (2014) (PubMed).
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- MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))
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别名
- MARCH5
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背景
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Background Information: MARCH5 is an ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2) and DRP1 (DNM1L). MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2, MIM 608507) and DRP1 (DNM1L, MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1502 AK000452.1 3-1504 1503-1863 BC015480.1 1463-1823 1864-1901 BE393612.1 438-475 1902-3713 BC015480.1 1852-3663 3714-3941 BC015480.1 3669-3896
Gene Name: Membrane-associated ring finger (C3HC4) 5
Alternative Symbols: MITOL, MARCH5, RNF153, MARCH-V
Protein Name: E3 ubiquitin-protein ligase MARCH5
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分子量
- 31kDa
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基因ID
- 54708
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NCBI登录号
- NP_060294
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UniProt
- Q9NX47
抗原
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