RNF19A 抗体 (N-Term)
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北京 101111
Quick Overview for RNF19A 抗体 (N-Term) (ABIN2774733)
抗原
See all RNF19A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- RNF19A Antibody - N-terminal region
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序列
- IFSTNTSSDN GLTSISKQIG DFIECPLCLL RHSKDRFPDI MTCHHRSCVD
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against RNF19A. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RNF19A
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anti-Ring Finger Protein 19A (RNF19A) (N-Term) antibody
RNF19A 适用: 人, 小鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 19A (RNF19A) (AA 108-157) antibodyRNF19A 适用: 人, 小鼠, Cow, 犬, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 19A (RNF19A) (AA 741-825) antibodyRNF19A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 19A (RNF19A) (AA 739-837) antibodyRNF19A 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4E4 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43197-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- RNF19A (Ring Finger Protein 19A (RNF19A))
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别名
- RNF19A
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背景
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Background Information: RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB.The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.
Gene Name: Ring finger protein 19A, E3 ubiquitin protein ligase
Alternative Symbols: RNF19
Protein Name: E3 ubiquitin-protein ligase RNF19A
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分子量
- 91kDa
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基因ID
- 25897
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NCBI登录号
- NP_056250
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UniProt
- Q9NV58
抗原
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