RNF40 抗体 (C-Term)
Quick Overview for RNF40 抗体 (C-Term) (ABIN2774720)
抗原
See all RNF40 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- KLLREEKDEL GEQVLGLKSQ VDAQLLTVQK LEEKERALQG SLGGVEKELT
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against RNF40. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RNF40
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1001 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
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别名
- RNF40
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背景
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RNF40 contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.
Alias Symbols: BRE1B, DKFZp686K191, KIAA0661, MGC13051, RBP95, STARING
Protein Interaction Partner: UBE2A, UBC, SFR1, CCDC146, RNF20, AMOTL2, RNF40, UBE2I, UBE2B, MSL1, MSL2, PAF1, HIST2H2BE, CDK9, MDM2, USP15, HSP90AA1, NOTCH1, UBE2E1, RB1, ITSN1, CDC73, SUMO2, ATM, AR, TERF2, TERF1, WAC, ZNF451, TRIM51, UBE2L6, NCBP1, STX1A,
Protein Size: 1001 -
分子量
- 114 kDa
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基因ID
- 9810
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NCBI登录号
- NM_014771, NP_055586
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UniProt
- O75150
抗原
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