FBXO5 抗体 (C-Term)
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北京 101111
Quick Overview for FBXO5 抗体 (C-Term) (ABIN2774700)
抗原
See all FBXO5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- FBXO5 Antibody - C-terminal region
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序列
- ASVQKSAAQT SLKKDAQTKL SNQGDQKGST YSRHNEFSEV AKTLKKNESL
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预测反应
- Dog: 85%, Human: 100%, Pig: 79%, Rabbit: 92%
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产品特性
- This is a rabbit polyclonal antibody against FBXO5. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human FBXO5
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anti-F-Box Protein 5 (FBXO5) (AA 1-250) antibody
FBXO5 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal EMI1-1176 unconjugated
anti-F-Box Protein 5 (FBXO5) (AA 326-375) antibodyFBXO5 适用: 人, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 5 (FBXO5) (C-Term) antibodyFBXO5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 5 (FBXO5) (AA 192-221) antibodyFBXO5 适用: 人 WB 宿主: 兔 Polyclonal RB30346 unconjugated
anti-F-Box Protein 5 (FBXO5) (AA 358-446) antibodyFBXO5 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box Protein 5 (FBXO5) (AA 358-446) antibodyFBXO5 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 5H7 unconjugated
anti-F-Box Protein 5 (FBXO5) (AA 1-250) antibodyFBXO5 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal EMI1-1176 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43125-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles." in: PLoS pathogens, Vol. 3, Issue 7, pp. e104, (2007) (PubMed).
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- FBXO5 (F-Box Protein 5 (FBXO5))
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别名
- FBXO5
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背景
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Background Information: FBXO5 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class and is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: F-box protein 5
Alternative Symbols: EMI1, FBX5, Fbxo31
Protein Name: F-box only protein 5
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分子量
- 50kDa
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基因ID
- 26271
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NCBI登录号
- NP_036309
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UniProt
- Q9UKT4
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途径
- Mitotic G1-G1/S Phases
抗原
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